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DMT-2'-O-Me-U-CE Phosphoramidite Amount/Package:0.5g / 30mL screwed bottle-28 High purity

SKU: 67246986395

4.5
USD19.00 USD64.00

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Ships within 48 hours · Estimated delivery Jul 26 - Jul 31

Description

High purity

The 100 mM disodium salt solution provides 5moU in a highly soluble

Lars Kongsbak

Therapeutic oligonucleotides

Synthesis of RNA oligonucleotides using 2'-F phosphoramidite increases the nuclease resistance and binding affinity of duplexes formed with complementary sequences

DMT-2'-O-Me-U-CE Phosphoramidite Amount/Package:0.5g / 30mL screwed bottle-28 High purityDMT 2' O Me U CE Phosphoramidite is a 2' OMe phosphoramidite monomer used for solid phase oligonucleotide synthesis. It contains a 5' dimethoxytrityl (DMT) protecting group for 5' hydroxyl protection, a uracil, a cyanoethyl (CE) protecting group on cytosine, and a 2' O methyl (2' OMe) ribose modification The 2' OMe modification improves duplex stability, reduces immunogenicity, and significantly increases resistance to nucleases Applications siRNA

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