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Resistance to decapping enzymes
Used in IVT systems to generate high-quality and modified mRNA with improved performance
" Molecular Pharmacology 84
and calibration of nucleotide quantification assays
Steric-blocking ASO
2'-O-4'-C-Locked-G(dmf) Phosphoramidite Amount/Package:10g / 240mL screwed bottle Resistance to decapping enzymes2 O 4 C Locked G(dmf) Phosphoramidite is a locked nucleic acid (LNA) phosphoramidite monomer for solid phase oligonucleotide synthesis. It contains a bicyclic ribose in which a methylene bridge connects the 2 oxygen (O) and 4 carbon (C), locking the sugar in a C3 endo conformation. It also contains a guanine (G) with dimethylformamidyl (dmf) base protection, a 5 dimethoxytrityl (DMT) group for 5 hydroxyl protection, and a cyanoethyl (CE) protecting
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