UA-Glo® BRET Ligand 618 CD Molecular Antigen Soluble ACE2 lowers blood pressure

Soluble ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II (a vasoconstrictor peptide) into angiotensin (1–7) (a vasodilator) which in turns binds to MasR receptors creating localized vasodilation and hence decreasing blood pressure

but homodimers of p40 have been shown to bind IL-12 receptors and are IL-12 antagonists

then gently mix (concentration is 500pg/mL)

CLA1 Accession Q8WTV0 Amino Acid Sequence Protein sequence (Q8WTV0

GABRA1 (gamma-aminobutyric acid type A receptor subunit alpha1) is the most abundant α-subunit of the pentameric GABA_A receptor

UA-Glo® BRET Ligand 618 CD Molecular Antigen Soluble ACE2 lowers blood pressureProduct Specification Stability & Storage Dry ice transportation. Store away from light at 20C or below, and it is recommended to store for long term (>3 months) at 80C with a shelf life of 12 months. Background UA Glo BRET Ligand 618 is a red emitting fluorescent dye after excitation, which can serve as an energy acceptor in BRET (Bioluminescence Resonance Energy Transfer) experiments, particularly suitable for detecting protein protein interactions