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TPH-1 Recombinant Rabbit mAb (S-2287-143) Protease Series promoting NFE2L2/NRF2 nuclear accumulation and

SKU: 18132102864

4.5
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Description

promoting NFE2L2/NRF2 nuclear accumulation and expression of phase II detoxifying enzymes

FGFR2b is a member of the fibroblast growth factor receptor family

Host Mouse Antigen Mouse CD3 Synonyms T-cell surface glycoprotein CD3 zeta chain

where it transduces signals from the PI3K pathway through dual phosphorylation at T309 by PDK1 and S474 by mTORC2 to adopt an active conformation that phosphorylates >100 substrates—key among them GSK3β

which is then methylated to melatonin by S-adenosylmethionine catalyzed by acetyl-serotonin O-methyltransferase

TPH-1 Recombinant Rabbit mAb (S-2287-143) Protease Series promoting NFE2L2/NRF2 nuclear accumulation andProduct Specification Host Rabbit Antigen TPH 1 Synonyms Tryptophan 5 hydroxylase 1; Tryptophan 5 monooxygenase 1; TPH; TPRH; TRPH; TPH1 Immunogen Synthetic Peptide Accession P17752 Clone Number S 2287 143 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Predicted Reactivity Rb Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03%

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